Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570195 | 0.84 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL8081036 | 0.83 | P2RX7 (0.52) | P2RX7 | |
| SCHEMBL7084381 | 0.80 | P2RX7 (0.47) | P2RX7 | |
| SCHEMBL7690936 | 0.80 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL7517360 | 0.76 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL7514220 | 0.75 | P2RX7 (0.68) | P2RX7 | |
| SCHEMBL7864022 | 0.75 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL8080894 | 0.75 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL6497265 | 0.75 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL4095273 | 0.75 | P2RX7 (0.56) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036059-A1 | ADAMANTANE DERIVATIVES | AstraZeneca UK Limited (GB) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999029661-A1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LIMITED (GB) | 1999-06-17 | — | — | WO | disclosed |