Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 15/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568584 | 0.84 | P2RX7 (0.62) | P2RX7MEN1KMT2AALDH1A1 | |
| SCHEMBL7690936 | 0.80 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL7862766 | 0.75 | MEN1 (0.43) | P2RX7MEN1KMT2AALDH1A1CNR2 | |
| SCHEMBL8086064 | 0.75 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL8080956 | 0.73 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL8071736 | 0.72 | KDM4E (0.46) | P2RX7MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7517360 | 0.71 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL8071740 | 0.71 | NPC1 (0.53) | P2RX7MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6497265 | 0.70 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL8080894 | 0.70 | P2RX7 (0.56) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303659-B2 | Compounds | ASTRAZENECA AB (SE) | 2001-10-16 | — | — | US | disclosed |