Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CETP | P11597 | 3/20 | 0.47 |
| ▸ | GMNN | O75496 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.47 |
| ▸ | CCR6 | P51684 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | UBE2N | P61088 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23924852 | 0.96 | MEN1 (0.47) | MEN1KMT2ACYP3A4SPHK2SPHK1 | |
| SCHEMBL31521534 | 0.96 | MEN1 (0.47) | MEN1KMT2ACYP3A4SPHK2SPHK1 | |
| SCHEMBL23924850 | 0.96 | MEN1 (0.47) | MEN1KMT2ACYP3A4SPHK2SPHK1 | |
| SCHEMBL20500716 | 0.95 | MEN1 (0.50) | MEN1KMT2ACYP3A4SPHK2SPHK1 | |
| SCHEMBL11124750 | 0.93 | FAAH (0.50) | MEN1KMT2ACYP3A4SPHK2SPHK1 | |
| SCHEMBL9062496 | 0.93 | MEN1 (0.44) | MEN1KMT2ACYP3A4SPHK2SPHK1 | |
| SCHEMBL4298120 | 0.93 | FAAH (0.50) | MEN1KMT2ACYP3A4SPHK2SPHK1 | |
| SCHEMBL4295285 | 0.93 | FAAH (0.50) | MEN1KMT2ACYP3A4SPHK2SPHK1 | |
| SCHEMBL28825728 | 0.91 | MEN1 (0.47) | MEN1KMT2ACYP3A4SPHK2SPHK1 | |
| SCHEMBL28468110 | 0.91 | TSHR (0.48) | MEN1KMT2ACYP3A4SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678115-B1 | PROCESS FOR PREPARING FUNCTIONAL GROUP-CONTAINING OLEFINIC COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2011-11-16 | — | — | EP | disclosed |
| US-20110264206-A1 | Prosthetic Valve with Sealing Members and Methods of Use Thereof | MEDTRONIC, INC. (US) | 2011-10-27 | — | — | US | disclosed |