Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | BLM | P54132 | 4/20 | 0.46 |
| ▸ | GMNN | O75496 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | CETP | P11597 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.46 |
| ▸ | CCR6 | P51684 | 2/20 | 0.46 |
| ▸ | UBE2N | P61088 | 2/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11124750 | 1.00 | FAAH (0.50) | FAAHTRPV1KMT2AMEN1CYP3A4 | |
| SCHEMBL4298120 | 1.00 | FAAH (0.50) | FAAHTRPV1KMT2AMEN1CYP3A4 | |
| SCHEMBL20500716 | 0.98 | MEN1 (0.50) | FAAHTRPV1KMT2AMEN1CYP3A4 | |
| SCHEMBL28049385 | 0.94 | MEN1 (0.47) | FAAHTRPV1KMT2AMEN1CYP3A4 | |
| SCHEMBL28049415 | 0.94 | MEN1 (0.47) | FAAHTRPV1KMT2AMEN1CYP3A4 | |
| SCHEMBL28825728 | 0.94 | MEN1 (0.47) | FAAHTRPV1KMT2AMEN1CYP3A4 | |
| SCHEMBL808616 | 0.93 | MEN1 (0.50) | FAAHTRPV1KMT2AMEN1CYP3A4 | |
| SCHEMBL9062496 | 0.91 | MEN1 (0.44) | FAAHTRPV1KMT2AMEN1CYP3A4 | |
| SCHEMBL25132302 | 0.91 | FAAH (0.68) | FAAHTRPV1KMT2AMEN1CYP3A4 | |
| SCHEMBL31521534 | 0.89 | MEN1 (0.47) | FAAHTRPV1KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120177698-A1 | AGGREGATES WITH INCREASED DEFORMABILITY, COMPRISING AT LEAST THREE AMPHIPATS, FOR IMPROVED TRANSPORT THROUGH SEMI-PERMEABLE BARRIERS AND FOR THE NON-INVASIVE DRUG APPLICATION IN VIVO, ESPECIALLY THROUGH THE SKIN | CEVC GREGOR (DE) | 2012-07-12 | — | — | US | disclosed |
| US-20090155235-A1 | AGGREGATES WITH INCREASED DEFORMABILITY, COMPRISING AT LEAST THREE AMPHIPATS, FOR IMPROVED TRANSPORT THROUGH SEMI-PERMEABLE BARRIERS AND FOR THE NON-INVASIVE DRUG APPLICATION IN VIVO, ESPECIALLY THROUGH THE SKIN | IDEA AG (DE) | 2009-06-18 | — | — | US | disclosed |
| US-7473432-B2 | NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery | IDEA AG (DE) | 2009-01-06 | — | — | US | disclosed |
| US-20070042030-A1 | Preparation for the application of agents in mini-droplets | IDEA AG (DE) | 2007-02-22 | — | — | US | disclosed |
| US-6165500-A | Preparation for the application of agents in mini-droplets | IDEA AG (DE) | 2000-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120177698-A1 | AGGREGATES WITH INCREASED DEFORMABILITY, COMPRISING AT LEAST THREE AMPHIPATS, FOR IMPROVED TRANSPORT THROUGH SEMI-PERMEABLE BARRIERS AND FOR THE NON-INVASIVE DRUG APPLICATION IN VIVO, ESPECIALLY THROUGH THE SKIN | CUTA, ABCG2, ABCB11 | FAAH 4468/4885TRPV1 1287/4885KMT2A 3680/4885 |
| US-20090155235-A1 | AGGREGATES WITH INCREASED DEFORMABILITY, COMPRISING AT LEAST THREE AMPHIPATS, FOR IMPROVED TRANSPORT THROUGH SEMI-PERMEABLE BARRIERS AND FOR THE NON-INVASIVE DRUG APPLICATION IN VIVO, ESPECIALLY THROUGH THE SKIN | CUTA, ABCG2, PIGS | FAAH 3983/4885TRPV1 828/4885KMT2A 4133/4885 |
| US-20070042030-A1 | Preparation for the application of agents in mini-droplets | FABP4, NPC1L1, LIPA | FAAH 1314/4885TRPV1 1520/4885KMT2A 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.