SCHEMBL8086306

SCHEMBL8086306

CCCCCCCCc1cccc(Cc2cccc(C)c2)c1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.53
LIPG Q9Y5X9 3/20 0.53
CNR1 P21554 2/20 0.50
CNR2 P34972 2/20 0.50
TAAR1 Q96RJ0 1/20 0.50
PPARG P37231 3/20 0.46
PPARA Q07869 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8095815 1.00 LPL (0.53) LPLLIPGCNR1CNR2TAAR1
SCHEMBL8098390 1.00 LPL (0.53) LPLLIPGCNR1CNR2TAAR1
SCHEMBL8093858 0.98 TAAR1 (0.52) LPLLIPGCNR1CNR2TAAR1
SCHEMBL8096717 0.93 TAAR1 (0.53) LPLLIPGCNR1CNR2TAAR1
SCHEMBL9485795 0.93 LPL (0.59) LPLLIPGCNR1CNR2TAAR1
SCHEMBL8780379 0.93 LPL (0.59) LPLLIPGCNR1CNR2TAAR1
SCHEMBL11073651 0.93 LPL (0.59) LPLLIPGCNR1CNR2TAAR1
SCHEMBL105418 0.93 LPL (0.59) LPLLIPGCNR1CNR2TAAR1
SCHEMBL28041371 0.93 LPL (0.59) LPLLIPGCNR1CNR2TAAR1
SCHEMBL11069727 0.93 LPL (0.59) LPLLIPGCNR1CNR2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708077-B1 Diamino compounds and methods for preparing them CHISSO CORP (JP) 2000-12-27 EP disclosed
US-5663440-A Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1997-09-02 US disclosed
EP-0708077-A1 Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1996-04-24 EP disclosed