Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | LPL | P06858 | 2/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093858 | 0.95 | TAAR1 (0.52) | TAAR1CNR1CNR2LPLLIPG | |
| SCHEMBL8095815 | 0.93 | LPL (0.53) | TAAR1CNR1CNR2LPLLIPG | |
| SCHEMBL8086306 | 0.93 | LPL (0.53) | TAAR1CNR1CNR2LPLLIPG | |
| SCHEMBL8098390 | 0.93 | LPL (0.53) | TAAR1CNR1CNR2LPLLIPG | |
| SCHEMBL30869992 | 0.92 | TAAR1 (0.61) | TAAR1LPLLIPGHRH3SKP2 | |
| SCHEMBL167733 | 0.92 | TAAR1 (0.61) | TAAR1LPLLIPGHRH3SKP2 | |
| SCHEMBL5433566 | 0.90 | LPL (0.52) | LPLLIPGSKP2NPC1HPGD | |
| SCHEMBL8085161 | 0.89 | TAAR1 (0.57) | TAAR1HRH3DAOIDO1XIAP | |
| SCHEMBL8094986 | 0.86 | LPL (0.49) | LPLLIPGSKP2NPC1HPGD | |
| SCHEMBL598872 | 0.86 | TAAR1 (0.59) | TAAR1CNR1CNR2LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |