Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.44 |
| ▸ | TUBB | P07437 | 7/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145066 | 0.79 | GRIN2D (0.52) | KDM4EALDH1A1SMN1; SMN2TUBB4ATUBB | |
| SCHEMBL13847310 | 0.72 | DAO (0.62) | KDM4EALDH1A1SMN1; SMN2CYP1A2TNKS2 | |
| SCHEMBL7010909 | 0.70 | PDE3B (0.35) | SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL6343134 | 0.69 | KDM4E (0.62) | KDM4EALDH1A1SMN1; SMN2CYP1A2TNKS2 | |
| SCHEMBL7812029 | 0.69 | DAO (0.54) | KDM4EALDH1A1SMN1; SMN2CYP1A2TNKS2 | |
| SCHEMBL7007761 | 0.69 | MCL1 (0.33) | KDM4EALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL7013173 | 0.66 | TYMS (0.32) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9715631 | 0.65 | KDM4E (0.69) | KDM4EALDH1A1SMN1; SMN2CYP1A2TNKS2 | |
| SCHEMBL30623756 | 0.65 | KDM4E (0.69) | KDM4EALDH1A1SMN1; SMN2CYP1A2TNKS2 | |
| SCHEMBL18464567 | 0.65 | PDE9A (0.68) | KDM4EALDH1A1SMN1; SMN2PDGFRBFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015820-A | VIRICIDES; AIDS TREATMENT | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2000-01-18 | — | — | US | disclosed |