Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | KDM5A | P29375 | 3/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARD | Q03181 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2239409 | 0.83 | MAPT (0.32) | — | |
| SCHEMBL1908068 | 0.74 | CYP1A2 (0.46) | CYP1A2MAPK1SMN1; SMN2TSHRLMNA | |
| SCHEMBL27778773 | 0.72 | HRH3 (0.54) | HRH3CYP1A2MAPK1SMN1; SMN2TSHR | |
| SCHEMBL11626844 | 0.70 | HRH3 (0.56) | HRH3CYP1A2MAPK1SMN1; SMN2TSHR | |
| SCHEMBL561947 | 0.70 | TSHR (0.36) | TSHRLMNANFKB1PMP22TBXAS1 | |
| SCHEMBL27905837 | 0.69 | TSHR (0.52) | EPHX1TSHRLMNANFKB1PMP22 | |
| SCHEMBL6253569 | 0.69 | ITGB3 (0.33) | ITGB3ITGA2BTSHRLMNANFKB1 | |
| SCHEMBL30368493 | 0.69 | NAAA (0.39) | HRH3CYP1A2MAPK1SMN1; SMN2EPHX1 | |
| SCHEMBL1855290 | 0.68 | HRH3 (0.57) | HRH3CYP1A2MAPK1SMN1; SMN2TSHR | |
| SCHEMBL1865632 | 0.68 | HRH3 (0.57) | HRH3CYP1A2MAPK1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520568-B1 | Thermostable ethylene-carbon monoxide copolymer | DSM NV (NL) | 2000-11-22 | — | — | EP | disclosed |
| US-5286785-A | Heat resistance | DSM N.V. (NL) | 1994-02-15 | — | — | US | disclosed |
| EP-0520568-A2 | Thermostable ethylene-carbon monoxide copolymer | DSM N.V. (NL) | 1992-12-30 | — | — | EP | disclosed |