Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086921 | 1.00 | PTGS2 (0.42) | PTGS2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL9512129 | 0.87 | MAPT (0.50) | LMNAMEN1KMT2AKDM4ECYP3A4 | |
| SCHEMBL16957540 | 0.84 | LMNA (0.50) | PTGS2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL16957539 | 0.82 | LMNA (0.41) | PTGS2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL16954549 | 0.82 | KMT2A (0.46) | PTGS2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL16959066 | 0.81 | CYP4F2 (0.63) | PTGS2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL16959062 | 0.79 | MEN1 (0.50) | PTGS2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL16958977 | 0.78 | KMT2A (0.43) | PTGS2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL16950808 | 0.78 | MEN1 (0.49) | PTGS2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL16950805 | 0.78 | KMT2A (0.40) | PTGS2LMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166074-A | Pharmaceutical compositions | NORSK HYDRO A.S. (NO) | 2000-12-26 | — | — | US | claimed |
| US-6166074-A | Pharmaceutical compositions | NORSK HYDRO A.S. (NO) | 2000-12-26 | — | — | US | disclosed |
| EP-0738145-A1 | PHARMACEUTICAL COMPOSITIONS | NORSK HYDRO a.s. (NO) | 1996-10-23 | — | — | EP | disclosed |
| WO-1995018607-A1 | PHARMACEUTICAL COMPOSITIONS | NORSK HYDRO A.S (NO) | 1995-07-13 | — | — | WO | disclosed |