SCHEMBL8087287

SCHEMBL8087287

OCCCCOc1ccc(C=Cc2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 7/20 0.41
ALB P02768 1/20 0.38
APP P05067 10/20 0.37
CHRNA7 P36544 1/20 0.36
AHR P35869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8088778 0.99 PPARA (0.40) PPARAALBAPPCHRNA7
SCHEMBL8083921 0.96 PPARA (0.40) PPARAALBAPPCHRNA7AHR
SCHEMBL8083916 0.96 PPARA (0.40) PPARAALBAPPCHRNA7AHR
SCHEMBL195709 0.92 PPARA (0.38) PPARAAPPCHRNA7AHR
SCHEMBL8021069 0.92 PPARA (0.38) PPARAAPPCHRNA7AHR
SCHEMBL476729 0.87 AHR (0.48) CHRNA7AHR
SCHEMBL547497 0.87 AHR (0.48) CHRNA7AHR
SCHEMBL144241 0.86 AHR (0.50) AHR
SCHEMBL144242 0.86 AHR (0.50) AHR
SCHEMBL4956020 0.84 TUBB4A (0.50) CHRNA7AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859283-B1 4-(Alkoxyhydroxy)styryl triazine photoinitiators KODAK POLYCHROME GRAPHICS CO (US) 2000-11-02 EP disclosed
US-5837586-A LITHOGRAPHIC PRINTING PLATES RESISTANT TO SURFACE BLOOMING KODAK POLYCHROME GRAPHICS COMPANY, LTD. (US) 1998-11-17 US disclosed
EP-0859283-A1 4-(Alkoxyhydroxy)styryl triazine photoinitiators INTERNATIONAL PAPER COMPANY (US) 1998-08-19 EP disclosed