Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086261 | 0.96 | CYP1A2 (0.31) | LTA4HCYP1A2CYP2D6MAPK1CYP2C19 | |
| SCHEMBL8090438 | 0.90 | TAS1R3 (0.30) | — | |
| SCHEMBL27303530 | 0.87 | LTA4H (0.34) | LTA4H | |
| SCHEMBL6933362 | 0.86 | LTA4H (0.30) | LTA4H | |
| SCHEMBL921435 | 0.76 | KCNA3 (0.43) | LTA4HCYP1A2CYP2D6MAPK1CYP2C19 | |
| SCHEMBL1712248 | 0.75 | KCNA3 (0.42) | LTA4HCYP1A2CYP2D6MAPK1CYP2C19 | |
| SCHEMBL920697 | 0.75 | KCNA3 (0.42) | LTA4HCYP1A2CYP2D6MAPK1CYP2C19 | |
| SCHEMBL919376 | 0.75 | KCNA3 (0.42) | LTA4HCYP1A2CYP2D6MAPK1CYP2C19 | |
| SCHEMBL7337414 | 0.74 | PLAU (0.33) | LTA4H | |
| SCHEMBL5273491 | 0.73 | MCHR1 (0.36) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |