Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093734 | 0.94 | HTR2A (0.55) | HTR2ALIPGTLR8LMNAHTT | |
| SCHEMBL6547306 | 0.94 | HTR2A (0.59) | HTR2ALIPGTLR8CYP3A4CYP2D6 | |
| SCHEMBL8086301 | 0.94 | LIPG (0.53) | HTR2ALIPGTLR8CYP3A4SLC6A2 | |
| SCHEMBL6546225 | 0.92 | HTR2A (0.44) | HTR2ALIPGTLR8CYP3A4CYP2D6 | |
| SCHEMBL8099212 | 0.92 | HTR2A (0.44) | HTR2ALIPGTLR8CYP3A4CYP2D6 | |
| SCHEMBL8095272 | 0.92 | LIPG (0.56) | HTR2ALIPGTLR8CYP3A4SLC6A2 | |
| SCHEMBL8098698 | 0.92 | LIPG (0.56) | HTR2ALIPGTLR8CYP3A4SLC6A2 | |
| SCHEMBL8100866 | 0.92 | LIPG (0.56) | HTR2ALIPGTLR8CYP3A4SLC6A2 | |
| SCHEMBL9720016 | 0.91 | KEAP1 (0.56) | HTR2ALIPGCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8771661 | 0.89 | HTR2A (0.50) | HTR2ALIPGTLR8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |