Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8082109 | 0.86 | NPC1 (0.59) | NPC1RAB9APGRLMNAALDH1A1 | |
| SCHEMBL3455798 | 0.86 | NPC1 (0.59) | NPC1RAB9APGRLMNAALDH1A1 | |
| SCHEMBL2948683 | 0.83 | POLB (0.54) | POLBDGAT1LMNAALDH1A1MEN1 | |
| SCHEMBL8081340 | 0.82 | POLB (0.44) | NPC1RAB9APGRPOLBDGAT1 | |
| SCHEMBL8081350 | 0.82 | POLB (0.44) | NPC1RAB9APGRPOLBDGAT1 | |
| SCHEMBL3456233 | 0.81 | LMNA (0.74) | NPC1RAB9APGRLMNAALDH1A1 | |
| SCHEMBL3540640 | 0.81 | NPC1 (0.69) | NPC1RAB9APGRPOLBDGAT1 | |
| SCHEMBL18992826 | 0.79 | NPC1 (1.00) | NPC1RAB9APGRLMNAALDH1A1 | |
| SCHEMBL18992722 | 0.76 | NPC1 (0.69) | NPC1RAB9APGRPOLBLMNA | |
| SCHEMBL2945737 | 0.76 | MEN1 (0.53) | POLBDGAT1LMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702689-B1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS | ABBOTT LAB (US) | 2000-10-11 | — | — | EP | disclosed |
| EP-0702689-A4 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS | ABBOTT LAB (US) | 1997-10-22 | — | — | EP | disclosed |
| US-5616505-A | Haptens tracers, immunogens and antibodies for 3-phenyl-1-adamantaneacetic acids | ABBOTT LABORATORIES (US) | 1997-04-01 | — | — | US | disclosed |
| EP-0702689-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS | ABBOTT LABORATORIES (US) | 1996-03-27 | — | — | EP | disclosed |
| US-5424414-A | Haptens, tracers, immunogens and antibodies for 3-phenyl-1-adamantaneacetic acids | ABBOTT LABORATORIES (US) | 1995-06-13 | — | — | US | disclosed |
| WO-1994029329-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS | ABBOTT LABORATORIES (US) | 1994-12-22 | — | — | WO | disclosed |