Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081350 | 1.00 | POLB (0.44) | POLBNPC1RAB9ACYP1A2AKR1B1 | |
| SCHEMBL8081209 | 0.87 | MAPT (0.44) | NPC1RAB9APGRALDH1A1MAPT | |
| SCHEMBL8087323 | 0.82 | NPC1 (0.64) | POLBNPC1RAB9APGRALDH1A1 | |
| SCHEMBL17241148 | 0.73 | CYP1A2 (0.52) | POLBCYP1A2AKR1B1ALDH1A1MAPT | |
| SCHEMBL8082178 | 0.72 | LMNA (0.44) | NPC1ALDH1A1MAPTKMT2A | |
| SCHEMBL2948683 | 0.70 | POLB (0.54) | POLBALDH1A1KMT2ADGAT1 | |
| SCHEMBL8082109 | 0.70 | NPC1 (0.59) | NPC1RAB9APGRALDH1A1MAPT | |
| SCHEMBL3455798 | 0.70 | NPC1 (0.59) | NPC1RAB9APGRALDH1A1KMT2A | |
| SCHEMBL20591945 | 0.69 | MAPT (0.47) | POLBCYP1A2ALDH1A1MAPTKMT2A | |
| SCHEMBL6363105 | 0.67 | ALDH1A1 (0.50) | POLBNPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702689-B1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS | ABBOTT LAB (US) | 2000-10-11 | — | — | EP | disclosed |
| US-5616505-A | Haptens tracers, immunogens and antibodies for 3-phenyl-1-adamantaneacetic acids | ABBOTT LABORATORIES (US) | 1997-04-01 | — | — | US | disclosed |
| US-5424414-A | Haptens, tracers, immunogens and antibodies for 3-phenyl-1-adamantaneacetic acids | ABBOTT LABORATORIES (US) | 1995-06-13 | — | — | US | disclosed |