Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808659 | 0.92 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTHPGD | |
| SCHEMBL808533 | 0.90 | LMNA (0.42) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4345709 | 0.87 | KCNJ11 (0.40) | RAB9ANPC1MEN1KMT2AKDM4A | |
| SCHEMBL808743 | 0.87 | KCNJ11 (0.40) | RAB9ANPC1MEN1KMT2AKDM4A | |
| SCHEMBL808930 | 0.86 | KCNJ11 (0.44) | RAB9ANPC1MEN1KMT2AKDM4A | |
| SCHEMBL4338111 | 0.86 | MEN1 (0.41) | RAB9ANPC1MEN1KMT2AKDM4A | |
| SCHEMBL4340483 | 0.86 | KCNJ11 (0.42) | RAB9ANPC1MEN1KMT2AKDM4A | |
| SCHEMBL808765 | 0.85 | LMNA (0.39) | RAB9ANPC1MEN1KMT2AKDM4A | |
| SCHEMBL808597 | 0.83 | ALDH1A1 (0.43) | ALDH1A1LMNAHPGD | |
| SCHEMBL808793 | 0.83 | ALDH1A1 (0.40) | ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1593674-B1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2011-07-20 | — | — | EP | disclosed |