Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 16/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110894 | 0.91 | TP53 (0.52) | RAB9AMEN1KMT2ANPC1TP53 | |
| SCHEMBL8091754 | 0.91 | TP53 (0.52) | RAB9AMEN1KMT2ANPC1TP53 | |
| SCHEMBL8097600 | 0.86 | ALDH1A1 (0.39) | MEN1KMT2AMAPTGAA | |
| SCHEMBL13111118 | 0.80 | MEN1 (0.41) | RAB9AMEN1KMT2ANPC1TP53 | |
| SCHEMBL13110931 | 0.80 | MEN1 (0.41) | RAB9AMEN1KMT2ANPC1TP53 | |
| SCHEMBL13111110 | 0.77 | ALDH1A1 (0.45) | RAB9AKMT2ANPC1MAPTGAA | |
| SCHEMBL8093744 | 0.77 | ALDH1A1 (0.45) | RAB9AKMT2ANPC1MAPTGAA | |
| SCHEMBL13110919 | 0.77 | HDAC1 (0.43) | RAB9AKMT2ANPC1MAPTGAA | |
| SCHEMBL8091640 | 0.77 | MEN1 (0.46) | RAB9AMEN1KMT2ANPC1TP53 | |
| SCHEMBL13111017 | 0.67 | KMT2A (0.61) | RAB9AMEN1KMT2ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009015237-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-01-29 | — | — | WO | disclosed |