Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110791 | 0.89 | KMT2A (0.61) | MEN1KMT2ARAB9ATP53NPC1 | |
| SCHEMBL13111017 | 0.89 | KMT2A (0.61) | MEN1KMT2ARAB9ATP53NPC1 | |
| SCHEMBL8086107 | 0.84 | ACACB (0.39) | KMT2ARAB9ANPC1GAAALDH1A1 | |
| SCHEMBL8083255 | 0.79 | TP53 (0.63) | MEN1KMT2ARAB9ATP53NPC1 | |
| SCHEMBL13110842 | 0.79 | TP53 (0.63) | MEN1KMT2ARAB9ATP53NPC1 | |
| SCHEMBL13110733 | 0.78 | HDAC1 (0.57) | MEN1KMT2ARAB9ATP53NPC1 | |
| SCHEMBL13110969 | 0.78 | HDAC1 (0.57) | MEN1KMT2ARAB9ATP53NPC1 | |
| SCHEMBL8087602 | 0.77 | RAB9A (0.40) | MEN1KMT2ARAB9ATP53NPC1 | |
| SCHEMBL13110817 | 0.73 | HDAC1 (0.48) | MEN1KMT2ARAB9ATP53NPC1 | |
| SCHEMBL13111013 | 0.73 | HDAC1 (0.48) | MEN1KMT2ARAB9ATP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009015237-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-01-29 | — | — | WO | disclosed |