SCHEMBL8087920

CCC1(C(C/C=C/[C@@H]2[C@@H](C/C=C\CCCC(=O)O)[C@@H](Cl)C[C@H]2O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)CCC1

nearest known ligand 0.59

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	PTGER2	P43116	7/20	0.59

▸	PTGIR	P43119	2/20	0.59

▸	PTGER3	P43115	3/20	0.50

▸	PTGER1	P34995	1/20	0.50

▸	PTGER4	P35408	1/20	0.50

▸	PDE4D	Q08499	1/20	0.38

▸	TBXA2R	P21731	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7600274	1.00	PTGER2 (0.59)	PTGER2PTGIRPTGER3PTGER1PTGER4
SCHEMBL8090822	0.94	PTGER2 (0.54)	PTGER2PTGIRPTGER3PTGER1PTGER4
SCHEMBL8079368	0.91	PTGER2 (0.54)	PTGER2PTGIRPTGER3PTGER1PTGER4
SCHEMBL7583983	0.91	PTGER2 (0.54)	PTGER2PTGIRPTGER3PTGER1PTGER4
SCHEMBL8092628	0.89	PTGER2 (0.48)	PTGER2PTGIRPTGER3PTGER1PTGER4
SCHEMBL4734797	0.88	PTGER2 (0.47)	PTGER2PTGIRPTGER3PTGER1PTGER4
SCHEMBL4734798	0.88	PTGER2 (0.47)	PTGER2PTGIRPTGER3PTGER1PTGER4
SCHEMBL4734793	0.88	PTGER2 (0.47)	PTGER2PTGIRPTGER3PTGER1PTGER4
SCHEMBL7588668	0.85	PTGER2 (0.49)	PTGER2PTGIRPTGER3PTGER1PTGER4
SCHEMBL7590855	0.85	PTGER2 (0.49)	PTGER2PTGIRPTGER3PTGER1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6110969-A	Cycloalkyl-prostaglandin E2 derivatives	ONO PHARMACEUTICAL CO. LTD. (JP)	2000-08-29	—	—	US	disclosed