Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.34 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149810 | 0.86 | TSHR (0.39) | TSHRMAPK1ALDH1A1CYP3A4VCAM1 | |
| SCHEMBL8485253 | 0.85 | TDP1 (0.43) | MAPK1ALDH1A1CYP3A4VCAM1TDP1 | |
| SCHEMBL10956632 | 0.81 | MAPK1 (0.43) | TSHRMAPK1ALDH1A1CYP3A4VCAM1 | |
| SCHEMBL19136001 | 0.81 | SLC6A4 (0.37) | TSHRMAPK1ALDH1A1CYP3A4VCAM1 | |
| SCHEMBL7931545 | 0.79 | TDP1 (0.45) | MAPK1ALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL7021511 | 0.78 | HPGD (0.53) | MAPK1ALDH1A1TDP1ATMLMNA | |
| SCHEMBL10347965 | 0.77 | TDP1 (0.39) | MAPK1ALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL29653309 | 0.77 | TSHR (0.52) | TSHRMAPK1ALDH1A1CYP3A4VCAM1 | |
| SCHEMBL2477068 | 0.77 | TSHR (0.52) | TSHRMAPK1ALDH1A1CYP3A4VCAM1 | |
| SCHEMBL19554176 | 0.76 | TDP1 (0.40) | TSHRMAPK1ALDH1A1CYP3A4VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060432-A | SYNERGISTIC MIXTURE; CROPS, AGRICULTURE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0977760-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-02-09 | — | — | EP | disclosed |
| US-5883049-A | Hydantoin derivatives and herbicides containing said derivatives as active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1999-03-16 | — | — | US | disclosed |
| WO-1998047904-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-10-29 | — | — | WO | disclosed |
| EP-0862571-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-09-09 | — | — | EP | disclosed |
| CN-1175255-A | Hydantoin derivatives, process for producing the same and herbicides comprising the same as active ingredients | SAGAMI CHEM RES (JP) | 1998-03-04 | — | — | CN | disclosed |
| EP-0801068-A1 | HYDANTOIN DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND HERBICIDES COMPRISING THE SAME AS ACTIVE INGREDIENTS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1997-10-15 | — | — | EP | disclosed |
| EP-0638563-B1 | Aminoaryl-1,3-oxazin-2,4-diones | BAYER AG (DE) | 1997-10-15 | — | — | EP | disclosed |
| WO-1997015576-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-05-01 | — | — | WO | disclosed |
| US-5593944-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-14 | — | — | US | disclosed |
| EP-0638563-A1 | Aminoaryl-1,3-oxazin-2,4-diones | BAYER AG (DE) | 1995-02-15 | — | — | EP | disclosed |