Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087922 | 0.85 | TSHR (0.40) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL19554176 | 0.80 | TDP1 (0.40) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL11555859 | 0.77 | TDP1 (0.42) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL5166036 | 0.77 | PDGFRB (0.40) | TDP1ATMALDH1A1VCAM1ESPL1 | |
| SCHEMBL160626 | 0.76 | CYP3A4 (0.38) | TDP1ALDH1A1HPGDMAPK1CYP3A4 | |
| SCHEMBL45486 | 0.76 | TDP1 (0.60) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL19136001 | 0.75 | SLC6A4 (0.37) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL58080 | 0.74 | TDP1 (0.58) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL29403879 | 0.74 | TDP1 (0.58) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL78800 | 0.74 | ALDH1A1 (0.53) | TDP1ATMALDH1A1HIF1AVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883049-A | Hydantoin derivatives and herbicides containing said derivatives as active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0801068-A1 | HYDANTOIN DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND HERBICIDES COMPRISING THE SAME AS ACTIVE INGREDIENTS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1997-10-15 | — | — | EP | disclosed |
| EP-0413832-A1 | OXAZOLIDINEDIONE DERIVATIVES AND PRODUCTION THEREOF | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-02-27 | — | — | EP | disclosed |