Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.34 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19136001 | 0.86 | SLC6A4 (0.37) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL8485253 | 0.80 | TDP1 (0.43) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL9679957 | 0.79 | TDP1 (0.55) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL1019385 | 0.79 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL3843398 | 0.78 | CYP3A4 (0.42) | TDP1ALDH1A1CYP3A4HPGDTSHR | |
| SCHEMBL29648762 | 0.78 | CYP3A4 (0.42) | TDP1ALDH1A1CYP3A4HPGDTSHR | |
| SCHEMBL8087922 | 0.76 | TSHR (0.40) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL28688754 | 0.75 | MEN1 (0.44) | TDP1ALDH1A1HIF1ACYP3A4HPGD | |
| SCHEMBL3756498 | 0.75 | TDP1 (0.56) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL30257990 | 0.75 | TDP1 (0.56) | TDP1ATMALDH1A1HIF1AVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |