SCHEMBL8087968

SCHEMBL8087968

CC(=O)ON1C(=O)c2ccc(Br)c(Br)c2C1=O

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
KDR P35968 1/20 0.31
HPGD P15428 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5865397 0.76 NPC1 (0.50) ALDH1A1KDRHPGDTDP1NPC1
SCHEMBL2959931 0.73 DNMT1 (0.41) ALDH1A1HPGDRAB9A
SCHEMBL29838651 0.72 ALDH1A1 (0.47) ALDH1A1KDRHPGD
SCHEMBL859822 0.72 ALDH1A1 (0.47) ALDH1A1KDRHPGD
SCHEMBL6655099 0.71 ERCC1 (0.38) ALDH1A1HPGDTDP1NPC1RAB9A
SCHEMBL29000792 0.70 ANPEP (0.35) ALDH1A1KDRHPGDNPC1RAB9A
SCHEMBL19667896 0.70 ANPEP (0.38) ALDH1A1KDRHPGD
SCHEMBL13479732 0.69 TNF (0.38) ALDH1A1KDRHPGDTDP1NPC1
SCHEMBL13814011 0.69 CA9 (0.49) ALDH1A1HPGD
SCHEMBL3683888 0.69 S100A4 (0.31) HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6160128-A Tritioacetylating reagents and processes for preparation thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-12-12 US disclosed