Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634972 | 0.84 | KDM4E (0.54) | KDM4EALDH1A1ADORA2AHPGDADORA3 | |
| SCHEMBL8087960 | 0.83 | ALDH1A1 (0.39) | KDM4EALDH1A1ADORA2AHPGDADORA3 | |
| SCHEMBL8080587 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1ADORA2AHPGDADORA3 | |
| SCHEMBL5613348 | 0.75 | ALDH1A1 (0.73) | KDM4EALDH1A1ADORA2AHPGDADORA3 | |
| SCHEMBL8094143 | 0.74 | KDM4E (0.47) | KDM4EALDH1A1ADORA2AHPGDADORA3 | |
| SCHEMBL27512237 | 0.73 | KDM4E (0.52) | KDM4EALDH1A1ADORA2AHPGDADORA3 | |
| SCHEMBL1287104 | 0.72 | TOP1 (0.65) | KDM4EALDH1A1ADORA2AHPGDADORA3 | |
| SCHEMBL11101186 | 0.72 | TTR (0.72) | KDM4EALDH1A1ADORA2AHPGDADORA3 | |
| SCHEMBL2176042 | 0.72 | KDM4E (0.50) | KDM4EALDH1A1ADORA2AHPGDADORA3 | |
| SCHEMBL28633753 | 0.71 | KDM4E (0.50) | KDM4EALDH1A1ADORA2AHPGDADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6160128-A | Tritioacetylating reagents and processes for preparation thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-12-12 | — | — | US | disclosed |