SCHEMBL8088031

SCHEMBL8088031

CC1=CC(c2ccccc2)=C(C)C1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
CFTR P13569 1/20 0.33
GOPC Q9HD26 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
ALOX12 P18054 1/20 0.32
ACHE P22303 1/20 0.32
GRM6 O15303 1/20 0.31
ALOX5 P09917 1/20 0.31
CYP2A6 P11509 1/20 0.30
CYP2B6 P20813 1/20 0.30
SLC22A2 O15244 1/20 0.30
SLC22A1 O15245 1/20 0.30
SLC22A3 O75751 1/20 0.30
SLC6A4 P31645 1/20 0.30
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6407526 0.80 ALDH1A1 (0.34) ALDH1A1L3MBTL1LMNATSHRALOX12
Hydrochloric Acid SCHEMBL8618735 0.77 ALDH1A1 (0.31) ALDH1A1CFTRGOPC
SCHEMBL8079538 0.75 TP53 (0.33) L3MBTL1TSHR
Hydrochloric Acid SCHEMBL8361404 0.71
SCHEMBL20722299 0.65 ALDH1A1 (0.42) ALDH1A1CFTRGOPCL3MBTL1LMNA
SCHEMBL27546185 0.64 ALDH1A1 (0.40) ALDH1A1CFTRGOPCL3MBTL1LMNA
SCHEMBL4652308 0.61
Biphenyl SCHEMBL27656690 0.59 ALDH1A1 (0.69) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL9142020 0.59
Biphenyl SCHEMBL653702 0.58 ALDH1A1 (0.82) ALDH1A1LMNATSHRALOX12ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6046346-A Production of alkali metal cyclopentadienylide and production of dihalobis (η-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2000-04-04 US disclosed
EP-0926150-A2 Production of alkali metal cyclopentadienylide and production of dihalobis(eta-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide Honshu Chemical Industry Co. Ltd. (JP) 1999-06-30 EP disclosed