Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GRM6 | O15303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088031 | 0.80 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1LMNATSHRALOX12 | |
| Hydrochloric Acid SCHEMBL8618735 | 0.67 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL1824459 | 0.62 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1LMNATSHRALOX12 | |
| SCHEMBL27546185 | 0.62 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1LMNATSHRALOX12 | |
| SCHEMBL20663060 | 0.61 | CFTR (0.37) | ALDH1A1L3MBTL1LMNATSHRALOX12 | |
| SCHEMBL4849997 | 0.59 | TSHR (0.39) | ALDH1A1LMNATSHRALOX12ACHE | |
| SCHEMBL20722299 | 0.59 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1LMNATSHRALOX12 | |
| Biphenyl SCHEMBL27656690 | 0.58 | ALDH1A1 (0.69) | ALDH1A1GAASMN1; SMN2 | |
| Biphenyl SCHEMBL653702 | 0.57 | ALDH1A1 (0.82) | ALDH1A1LMNATSHRALOX12ACHE | |
| Biphenyl SCHEMBL7930008 | 0.56 | ACHE (0.79) | ALDH1A1L3MBTL1LMNATSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261497-A1 | Catalytic asymmetric hetero diels-alder reaction of a heteroaromatic C-nitroso dienophile: a novel method for synthesis of chiral non-racemic amino alcohols | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2005-11-24 | — | — | US | disclosed |
| WO-2005068457-A1 | CATALTYTIC ASYMMETRIC HETERO DIELS-ALDER REACTION OF A HETEROAROMATIC C-NITROSO DIENOPHILE: A NOVEL METHOD FOR SYNTHESIS OF CHIRAL NON-RACEMIC AMINO ALCOHOLS | UNIVERSITY OF CHICAGO (US) | 2005-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261497-A1 | Catalytic asymmetric hetero diels-alder reaction of a heteroaromatic C-nitroso dienophile: a novel method for synthesis of chiral non-racemic amino alcohols | ADH5, ADH1C, ADH1A | ALDH1A1 113/4885L3MBTL1 3276/4885LMNA 4351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.