Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | PRPS1 | P60891 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038637 | 0.86 | MAPT (0.57) | MAPTHSD17B10PRPS1LMNANPC1 | |
| SCHEMBL7877110 | 0.85 | LMNA (0.55) | MAPTHSD17B10PRPS1LMNANPC1 | |
| SCHEMBL8659266 | 0.85 | MAPT (0.53) | MAPTHSD17B10PRPS1LMNANPC1 | |
| SCHEMBL2797606 | 0.83 | PRPS1 (0.55) | MAPTHSD17B10PRPS1LMNANPC1 | |
| SCHEMBL13668156 | 0.80 | PRPS1 (0.50) | MAPTHSD17B10PRPS1LMNANPC1 | |
| SCHEMBL9597222 | 0.80 | KMT2A (0.51) | MAPTHSD17B10PRPS1LMNANPC1 | |
| SCHEMBL9570037 | 0.80 | LMNA (0.51) | MAPTHSD17B10PRPS1LMNANPC1 | |
| SCHEMBL3303214 | 0.80 | NPC1 (0.51) | MAPTHSD17B10PRPS1LMNANPC1 | |
| SCHEMBL30636878 | 0.79 | MAPT (0.50) | MAPTHSD17B10PRPS1LMNANPC1 | |
| SCHEMBL22135376 | 0.78 | MAPT (0.52) | MAPTHSD17B10LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680967-B1 | Erythromycin derivatives, their process of preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (FR) | 1998-10-14 | — | — | EP | claimed |
| US-6100404-A | Erythromycin compounds | HOECHST MARION ROUSSEL (FR) | 2000-08-08 | — | — | US | disclosed |
| EP-0680967-B1 | Erythromycin derivatives, their process of preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (FR) | 1998-10-14 | — | — | EP | disclosed |
| US-5635485-A | Erythromycin compounds | ROUSSEL UCLAF (FR) | 1997-06-03 | — | — | US | disclosed |
| EP-0680967-A1 | Erythromycin derivatives, their process of preparation and their use as medicaments | ROUSSEL-UCLAF (FR) | 1995-11-08 | — | — | EP | disclosed |