Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088256 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL27748314 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL11128936 | 0.81 | CYP1A2 (0.46) | ALDH1A1HPGDSMN1; SMN2LMNAMEN1 | |
| SCHEMBL27693488 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAEGFRMEN1 | |
| SCHEMBL12411256 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL17955311 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL14301368 | 0.78 | EGFR (0.38) | ALDH1A1MAPTLMNAEGFRMEN1 | |
| SCHEMBL8859065 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL12411252 | 0.74 | NPC1 (0.49) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL11206642 | 0.74 | NPC1 (0.49) | ALDH1A1HPGDMAPTNPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045868-A1 | HOMOPOLYMERS AND COPOLYMERS OF ETHYLENE | BP Chemicals Limited (GB) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999035174-A1 | HOMOPOLYMERS AND COPOLYMERS OF ETHYLENE | BP CHEMICALS LIMITED (GB) | 1999-07-15 | — | — | WO | disclosed |