SCHEMBL8088292

SCHEMBL8088292

CC1(C)NC(=O)C1(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18720246 0.81 TSHR (0.31)
SCHEMBL14446948 0.70
SCHEMBL9725347 0.69
SCHEMBL2107618 0.67 TSHR (0.32)
SCHEMBL6467970 0.65 POLB (0.38)
SCHEMBL2689498 0.60
SCHEMBL10830637 0.60 TSHR (0.32)
SCHEMBL22069 0.58
SCHEMBL4558728 0.58 LMNA (0.38)
SCHEMBL17975441 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0962449-A2 Method for producing 3-amino-2,2,3-trimethylbutanoate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-08 EP claimed
EP-0957090-A1 Method for producing 3,3,4,4-tetramethyl-2-azetidinone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-11-17 EP claimed
JP-11349563-A None JP disclosed
JP-11349563-A None JP disclosed
US-10463688-B2 Nylon-3 polymers active against Clostridium difficile WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2019-11-05 US disclosed
EP-2881384-B1 PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND TAISHO PHARMACEUTICAL CO LTD (JP) 2018-05-30 EP disclosed
US-20170000818-A1 NYLON-3 POLYMERS ACTIVE AGAINST CLOSTRIDIUM DIFFICILE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-01-05 US disclosed
US-20170000818-A1 NYLON-3 POLYMERS ACTIVE AGAINST CLOSTRIDIUM DIFFICILE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-01-05 US disclosed
US-9422240-B2 Partially saturated nitrogen-containing heterocyclic compound TAISHO PHARMACEUTICAL CO., LTD (JP) 2016-08-23 US disclosed
US-9422240-B2 Partially saturated nitrogen-containing heterocyclic compound TAISHO PHARMACEUTICAL CO., LTD (JP) 2016-08-23 US disclosed
US-9422240-B2 Partially saturated nitrogen-containing heterocyclic compound TAISHO PHARMACEUTICAL CO., LTD (JP) 2016-08-23 US disclosed
JP-H11349563-A PRODUCTION OF 3,3,4,4-TETRAMETHYL-2-AZETIDINONE SUMITOMO CHEM CO LTD 1999-12-21 JP disclosed
JP-H11349563-A PRODUCTION OF 3,3,4,4-TETRAMETHYL-2-AZETIDINONE SUMITOMO CHEM CO LTD 1999-12-21 JP disclosed
EP-0962449-A2 Method for producing 3-amino-2,2,3-trimethylbutanoate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-08 EP disclosed
EP-0962449-A2 Method for producing 3-amino-2,2,3-trimethylbutanoate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-08 EP disclosed
EP-0957090-A1 Method for producing 3,3,4,4-tetramethyl-2-azetidinone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-11-17 EP disclosed
EP-0957090-A1 Method for producing 3,3,4,4-tetramethyl-2-azetidinone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-11-17 EP disclosed
EP-0957090-A1 Method for producing 3,3,4,4-tetramethyl-2-azetidinone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-11-17 EP disclosed
EP-0379416-B1 Azabicycloheptene derivatives and their salts, process for their preparation, their use as medicaments and compositions containing them ROUSSEL UCLAF (FR) 1995-03-08 EP disclosed
EP-0379416-A2 Azabicycloheptene derivatives and their salts, process for their preparation, their use as medicaments and compositions containing them ROUSSEL-UCLAF (FR) 1990-07-25 EP disclosed