Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765940 | 1.00 | PLA2G4B (0.59) | PLA2G4BL3MBTL1LMNAPPARAFFAR1 | |
| SCHEMBL10290140 | 1.00 | PLA2G4B (0.59) | PLA2G4BL3MBTL1LMNAPPARAFFAR1 | |
| SCHEMBL10207303 | 0.98 | LMNA (0.61) | PLA2G4BL3MBTL1LMNAPPARAFFAR1 | |
| SCHEMBL10207287 | 0.93 | LMNA (0.63) | PLA2G4BL3MBTL1LMNAPPARAFFAR1 | |
| SCHEMBL8277617 | 0.88 | L3MBTL1 (0.68) | PLA2G4BL3MBTL1LMNAFFAR1MEN1 | |
| SCHEMBL29141429 | 0.88 | PPARA (0.71) | PLA2G4BL3MBTL1PPARAFFAR1ALB | |
| SCHEMBL21073528 | 0.88 | PPARA (0.71) | PLA2G4BL3MBTL1PPARAFFAR1ALB | |
| SCHEMBL31448424 | 0.88 | PPARA (0.71) | PLA2G4BL3MBTL1PPARAFFAR1ALB | |
| SCHEMBL14162908 | 0.87 | LMNA (0.69) | PLA2G4BL3MBTL1LMNAPPARAFFAR1 | |
| SCHEMBL12086480 | 0.87 | LMNA (0.69) | PLA2G4BL3MBTL1LMNAPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048989-A | PARASITICIDES AND ANTIBROTOZOA AGENTS | WASHINGTON UNIVERSITY (US) | 2000-04-11 | — | — | US | disclosed |
| US-6025511-A | A MYRISTIC ACID SELECTED ANALOGS FOR INHIBITING THE BIOSYNTHESIS OF THE GLYCOSYL PHOSPHATIDYLINOSITOL (GPI) ANCHOR OF THE PARASITE | WASHINGTON UNIVERSITY (US) | 2000-02-15 | — | — | US | disclosed |
| US-6001869-A | CONTACTING THE PARASITE WITH 2-THIENYL-UNDECENOIC ACID/10-/ | WASHINGTON UNIVERSITY (US) | 1999-12-14 | — | — | US | disclosed |
| US-5998642-A | Thienyl-containing fatty acid glycosyl phosphatidylinosital analogues used for inhibiting parasitic activity | WASHINGTON UNIVERSITY (US) | 1999-12-07 | — | — | US | disclosed |
| US-5760259-A | MYRISTIC ACID DERIVATIVES CAPABLE OF INHIBITING BIOSYNTHESIS OF PARASITE'S ANCHORING GROUP | WASHINGTON UNIVERSITY (US) | 1998-06-02 | — | — | US | disclosed |
| US-5747537-A | Method of inhibiting parasitic activity | WASHINGTON UNIVERSITY (US) | 1998-05-05 | — | — | US | disclosed |