Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.60 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.54 |
| ▸ | NEK2 | P51955 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088551 | 0.92 | EPHX2 (0.62) | EPHX2GPR119NEK2HRH3PDE4A | |
| SCHEMBL8081375 | 0.89 | EPHX2 (0.59) | EPHX2GPR119NEK2HRH3PDE4A | |
| SCHEMBL8088611 | 0.87 | EPHX2 (0.57) | EPHX2GPR119NEK2HRH3PDE4A | |
| SCHEMBL7335803 | 0.86 | GPR119 (0.52) | EPHX2GPR119NEK2HRH3PDE4A | |
| SCHEMBL31071566 | 0.85 | GPR119 (0.58) | EPHX2GPR119HRH3CHEK2 | |
| SCHEMBL8088637 | 0.84 | GPR119 (0.57) | EPHX2GPR119NEK2HRH3CHEK2 | |
| SCHEMBL30272601 | 0.84 | GPR119 (0.57) | EPHX2GPR119NEK2HRH3PDE4A | |
| SCHEMBL20570501 | 0.84 | GPR119 (0.57) | EPHX2GPR119NEK2HRH3PDE4A | |
| SCHEMBL22265776 | 0.83 | GPR119 (0.66) | EPHX2GPR119NEK2HRH3PDE4A | |
| SCHEMBL31071590 | 0.82 | GPR119 (0.57) | EPHX2GPR119NEK2HRH3CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |