SCHEMBL8088581

SCHEMBL8088581

CC(C)(CO)N1C(=O)C=CC1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 7/20 0.37
ALDH1A1 P00352 4/20 0.37
NPSR1 Q6W5P4 3/20 0.37
BLM P54132 2/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
GMNN O75496 1/20 0.37
THPO P40225 1/20 0.37
PMP22 Q01453 1/20 0.37
GSK3A P49840 2/20 0.36
GSK3B P49841 2/20 0.36
HPGD P15428 3/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
WRN Q14191 1/20 0.32
HIF1A Q16665 1/20 0.32
FAAH O00519 4/20 0.32
HSP90AA1 P07900 2/20 0.31
HTT P42858 2/20 0.31
TLR9 Q9NR96 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14529642 0.83 MGLL (0.32) MGLLALDH1A1NPSR1BLMLMNA
SCHEMBL17924863 0.82 MGLL (0.34) MGLLALDH1A1NPSR1BLMLMNA
SCHEMBL18533846 0.80 MGLL (0.40) MGLLALDH1A1NPSR1BLMLMNA
SCHEMBL17122051 0.78 MGLL (0.44) MGLLALDH1A1NPSR1BLMLMNA
SCHEMBL17897015 0.77 MGLL (0.34) MGLLALDH1A1NPSR1BLMLMNA
SCHEMBL1578819 0.76 MGLL (0.37) MGLLALDH1A1NPSR1BLMLMNA
SCHEMBL21776243 0.76 MGLL (0.37) MGLLALDH1A1NPSR1BLMLMNA
SCHEMBL19491066 0.76 MGLL (0.37) MGLLALDH1A1NPSR1BLMLMNA
SCHEMBL11931904 0.76 MGLL (0.38) MGLLALDH1A1NPSR1BLMLMNA
SCHEMBL17924851 0.74 MGLL (0.41) MGLLALDH1A1NPSR1BLMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6165672-A Maleimide or alicyclic olefin-based monomers, copolymer resin of these monomers and photoresist using the resin HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2000-12-26 US claimed
US-5030739-A Formation Of Hydroperoxides Using An N-Hydroxydicarboxylic Acid Imide As Catalyst HOFFMAN-LA ROCHE INC. (US) 1991-07-09 US claimed
US-6165672-A Maleimide or alicyclic olefin-based monomers, copolymer resin of these monomers and photoresist using the resin HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2000-12-26 US disclosed
US-5030739-A Formation Of Hydroperoxides Using An N-Hydroxydicarboxylic Acid Imide As Catalyst HOFFMAN-LA ROCHE INC. (US) 1991-07-09 US disclosed
EP-0198351-B1 CATALYTIC OXIDATION WITH N-HYDROXYDICARBOXYLIC ACID IMIDES F. HOFFMANN-LA ROCHE AG (CH) 1989-10-18 EP disclosed
EP-0198351-A2 Catalytic oxidation with N-hydroxydicarboxylic acid imides F. HOFFMANN-LA ROCHE AG (CH) 1986-10-22 EP disclosed