Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 4/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18533846 | 0.80 | MGLL (0.40) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL17122051 | 0.78 | MGLL (0.44) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL22308525 | 0.77 | MGLL (0.34) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL19491066 | 0.76 | MGLL (0.37) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL8088581 | 0.76 | MGLL (0.37) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL1578819 | 0.76 | MGLL (0.37) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL22399175 | 0.74 | MGLL (0.46) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL17924851 | 0.74 | MGLL (0.41) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL18473664 | 0.74 | ALDH1A1 (0.32) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL22237558 | 0.73 | MGLL (0.34) | MGLLALDH1A1LMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3036231-B1 | SUBSTITUTED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | JUBILANT BIOSYS LTD (IN) | 2020-02-26 | — | — | EP | disclosed |