Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088877 | 0.84 | KMT2A (0.47) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL8088883 | 0.83 | KDM4E (0.47) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL8087960 | 0.74 | ALDH1A1 (0.39) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL8088824 | 0.74 | ALDH1A1 (0.39) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL21099252 | 0.73 | ERCC1 (0.63) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL7712333 | 0.70 | KDM4E (0.62) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL30448667 | 0.69 | GSK3B (0.59) | KMT2AALDH1A1MEN1HSD17B10MAPT | |
| SCHEMBL4366187 | 0.69 | GSK3B (0.59) | KMT2AALDH1A1MEN1HSD17B10MAPT | |
| SCHEMBL8219437 | 0.68 | KDM4E (0.56) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL3795231 | 0.67 | ALDH1A1 (0.51) | KMT2AKDM4EALDH1A1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6160128-A | Tritioacetylating reagents and processes for preparation thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-12-12 | — | — | US | claimed |
| US-6160128-A | Tritioacetylating reagents and processes for preparation thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-12-12 | — | — | US | disclosed |