Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | ADK | P55263 | 1/20 | 0.59 |
| ▸ | NCEH1 | Q6PIU2 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30448667 | 1.00 | GSK3B (0.59) | GSK3BADKNCEH1MAPTALDH1A1 | |
| SCHEMBL30710587 | 0.89 | MAPT (0.58) | GSK3BADKNCEH1MAPTALDH1A1 | |
| SCHEMBL12199931 | 0.89 | MAPT (0.58) | GSK3BADKNCEH1MAPTALDH1A1 | |
| SCHEMBL9138035 | 0.87 | GSK3B (0.48) | GSK3BADKNCEH1MAPTALDH1A1 | |
| SCHEMBL1939486 | 0.87 | GSK3B (0.49) | GSK3BADKNCEH1MAPTALDH1A1 | |
| SCHEMBL9138037 | 0.86 | GSK3B (0.47) | GSK3BADKNCEH1MAPTALDH1A1 | |
| SCHEMBL16237145 | 0.83 | MAPT (0.71) | NCEH1MAPTALDH1A1MEN1RAB9A | |
| SCHEMBL27994957 | 0.83 | NCEH1 (0.48) | GSK3BADKNCEH1MAPTALDH1A1 | |
| SCHEMBL10806722 | 0.82 | GSK3B (0.56) | GSK3BADKMAPTALDH1A1MEN1 | |
| SCHEMBL14118237 | 0.81 | NCEH1 (0.50) | GSK3BADKNCEH1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619003-B2 | Process for producing optically active compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-11-17 | — | — | US | disclosed |
| US-20060173210-A1 | Process for producing optically active compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173210-A1 | Process for producing optically active compound | ADH5, ADH1A, ADH4 | GSK3B 4095/4885ADK 1519/4885NCEH1 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.