Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 6/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | ESR1 | P03372 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3908652 | 0.86 | ABCC1 (0.70) | STSABCC4ABCC1LMNAESR1 | |
| SCHEMBL5158101 | 0.83 | ESR1 (0.70) | STSLMNAESR1MAPTKMT2A | |
| SCHEMBL17515286 | 0.82 | ABCC4 (0.56) | STSABCC4ABCC1LMNAESR1 | |
| SCHEMBL7612623 | 0.81 | LMNA (0.70) | STSABCC4ABCC1LMNAESR1 | |
| SCHEMBL11783196 | 0.81 | STS (0.69) | STSLMNAESR1MAPTKMT2A | |
| SCHEMBL11788270 | 0.80 | STS (0.67) | STSLMNAESR1MAPTKMT2A | |
| SCHEMBL11780732 | 0.80 | STS (0.67) | STSLMNAESR1MAPTKMT2A | |
| SCHEMBL17817385 | 0.80 | STS (0.67) | STSLMNAESR1MAPTKMT2A | |
| SCHEMBL17515288 | 0.79 | ABCC1 (0.58) | STSABCC4ABCC1LMNAESR1 | |
| SCHEMBL7096088 | 0.79 | ESR1 (0.68) | STSABCC4ABCC1LMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042354-A2 | ESTRONE SULFAMATE INHIBITORS OF ESTRONE SULFATASE, AND ASSOCIATED PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE | SRI INTERNATIONAL (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033858-A2 | ESTRONE SULFAMATE INHIBITORS OF ESTRONE SULFATASE, AND ASSOCIATED PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE | SRI INTERNATIONAL (US) | 1999-07-08 | — | — | WO | disclosed |