Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.52 |
| ▸ | FNTB | P49356 | 11/20 | 0.52 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097850 | 1.00 | FNTA (0.52) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL8098288 | 0.93 | FNTA (0.43) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL8088208 | 0.92 | FNTA (0.44) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL8095348 | 0.91 | KMT2A (0.51) | FNTAFNTBPGGT1BKDM4EMEN1 | |
| SCHEMBL8095365 | 0.90 | KDM4E (0.47) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL8097456 | 0.89 | FNTA (0.44) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL8103821 | 0.88 | FNTA (0.52) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL8088439 | 0.88 | FNTA (0.52) | FNTAFNTBPGGT1BKCNH2KDM4E | |
| SCHEMBL8097432 | 0.87 | FNTA (0.60) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL8095903 | 0.87 | CYP11B1 (0.45) | FNTAFNTBPGGT1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |