Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 12/20 | 0.60 |
| ▸ | FNTB | P49356 | 12/20 | 0.60 |
| ▸ | PGGT1B | P53609 | 8/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | RHOA | P61586 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097850 | 0.87 | FNTA (0.52) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL8088935 | 0.87 | FNTA (0.52) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL8088953 | 0.85 | FNTA (0.45) | FNTAFNTBPGGT1BKCNH2ALDH1A1 | |
| SCHEMBL8103720 | 0.84 | FNTA (0.46) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8097456 | 0.84 | FNTA (0.44) | FNTAFNTBPGGT1BKCNH2ALDH1A1 | |
| SCHEMBL8095915 | 0.84 | FNTA (0.45) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8088396 | 0.84 | FNTA (0.45) | FNTAFNTBPGGT1BKCNH2ALDH1A1 | |
| SCHEMBL8104343 | 0.84 | FAAH (0.48) | FNTAFNTBPGGT1B | |
| SCHEMBL8097436 | 0.83 | FNTA (0.67) | FNTAFNTBPGGT1BKCNH2ALDH1A1 | |
| SCHEMBL8437476 | 0.83 | FNTA (0.67) | FNTAFNTBPGGT1BKCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |