Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915197 | 0.95 | FFAR4 (0.53) | FFAR4FFAR1KCNH2L3MBTL1TDP1 | |
| SCHEMBL13886127 | 0.89 | FFAR4 (0.51) | FFAR4FFAR1KCNH2L3MBTL1TDP1 | |
| SCHEMBL16542331 | 0.85 | KCNH2 (0.46) | FFAR4FFAR1KCNH2L3MBTL1TDP1 | |
| SCHEMBL8097212 | 0.84 | KCNH2 (0.45) | FFAR4FFAR1KCNH2L3MBTL1TDP1 | |
| SCHEMBL13886150 | 0.84 | L3MBTL1 (0.56) | FFAR4FFAR1KCNH2L3MBTL1TDP1 | |
| SCHEMBL3248092 | 0.82 | FFAR4 (0.55) | FFAR4FFAR1TDP1 | |
| SCHEMBL10791043 | 0.82 | FFAR1 (0.54) | FFAR4FFAR1 | |
| SCHEMBL13886119 | 0.81 | FFAR4 (0.44) | FFAR4FFAR1 | |
| SCHEMBL4668893 | 0.81 | FFAR4 (0.49) | FFAR4FFAR1 | |
| SCHEMBL8103430 | 0.81 | FFAR4 (0.56) | FFAR4FFAR1KCNH2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007372-B1 | DIALKYL ETHER DELIVERY AGENTS | EMISPHERE TECH INC (US) | 2015-03-04 | — | — | EP | disclosed |
| US-20090092580-A1 | DIALKYL ETHER DELIVERY AGENTS | EMISPHERE TECHNOLOGIES INC. (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090092580-A1 | DIALKYL ETHER DELIVERY AGENTS | EMISPHERE TECHNOLOGIES INC. (US) | 2009-04-09 | — | — | US | disclosed |
| WO-2007121471-A2 | DIALKYL ETHER DELIVERY AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-10-25 | — | — | WO | disclosed |
| US-6080869-A | Benzothiazolone derivatives | ASTRA PHARMACEUTICALS LIMITED (GB) | 2000-06-27 | — | — | US | disclosed |
| EP-0850232-B1 | BENZOTHIAZOLONE DERIVATIVES | ASTRA PHARMA PROD (GB) | 2000-03-15 | — | — | EP | disclosed |
| US-6008365-A | ADRENORECEPTOR AGONISTS AND DOPAMINE DA2-RECEPTOR AGONISTS, USEFUL IN THE TREATMENT OF OBSTRUCTIVE AIRWAY DISEASES | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-12-28 | — | — | US | disclosed |
| US-5977384-A | Benzothiazolone derivatives | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-11-02 | — | — | US | disclosed |
| US-5973167-A | Intermediates for making benzothiazolone derivatives | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-10-26 | — | — | US | disclosed |
| US-5846989-A | Benzothiazolone derivatives | ASTRA PHARMACEUTICALS LIMITED (GB) | 1998-12-08 | — | — | US | disclosed |
| EP-0850232-A1 | BENZOTHIAZOLONE DERIVATIVES | Astra Pharmaceuticals Limited (GB) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997010227-A1 | BENZOTHIAZOLONE DERIVATIVES | ASTRA PHARMACEUTICALS LIMITED (GB) | 1997-03-20 | — | — | WO | disclosed |
| US-4649160-A | HYPOTENSIVE, ANTIARRHYTHMIA, ADRENERGIC BLOCKING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1987-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090092580-A1 | DIALKYL ETHER DELIVERY AGENTS | LIPA, SLC10A1, ABCB11 | FFAR4 1213/4885FFAR1 1337/4885KCNH2 4356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.