Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 1/20 | 0.47 | |
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 13/20 | 0.41 |
| ▸ | NPY1R | P25929 | 9/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.41 |
| ▸ | NPY2R | P49146 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1694377 | 0.92 | NPY4R (0.49) | PDFSSTR3NPY4RNPY1RNPY5R | |
| SCHEMBL1694104 | 0.92 | NPY4R (0.49) | PDFSSTR3NPY4RNPY1RNPY5R | |
| SCHEMBL4799804 | 0.92 | NPY4R (0.49) | PDFSSTR3NPY4RNPY1RNPY5R | |
| Hydrochloric Acid SCHEMBL1259758 | 0.91 | NPY4R (0.49) | PDFSSTR3NPY4RNPY1RNPY5R | |
| Hydrochloric Acid SCHEMBL6703991 | 0.91 | NPY4R (0.49) | PDFSSTR3NPY4RNPY1RNPY5R | |
| SCHEMBL29699868 | 0.90 | PDF (0.47) | PDFSSTR3NPY4RNPY1RNPY5R | |
| SCHEMBL11374268 | 0.89 | PDF (0.49) | PDFSSTR3NPY4RNPY1RNPY5R | |
| SCHEMBL8723156 | 0.89 | PDF (0.52) | PDFSSTR3NPY4RNPY1RNPY5R | |
| SCHEMBL5756647 | 0.88 | PDF (0.45) | PDFSSTR3NPY4RNPY1RNPY5R | |
| SCHEMBL8722659 | 0.87 | PDF (0.48) | PDFSSTR3NPY4RNPY1RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045862-A1 | POLYPEPTIDES, DNA CODING THEREFOR, FORMULATIONS THEREOF, AND THEIR USE IN INHIBITING FACTOR XII ACTIVATION | Bio-Discovery Limited (GB) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999036439-A1 | POLYPEPTIDES, DNA CODING THEREFOR, FORMULATIONS THEREOF, AND THEIR USE IN INHIBITING FACTOR XII ACTIVATION | BIO-DISCOVERY LIMITED (GB) | 1999-07-22 | — | — | WO | disclosed |