Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CFD | P00746 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268449 | 1.00 | CYP3A4 (0.47) | CYP3A4ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL31268445 | 0.85 | CYP3A4 (0.47) | CYP3A4ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL28661214 | 0.82 | CFD (0.59) | CYP3A4ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL987450 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4ETSHRGAARAB9A | |
| SCHEMBL12094224 | 0.82 | TSHR (0.60) | CYP3A4ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL15046532 | 0.81 | ALDH1A1 (0.57) | CYP3A4ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL511275 | 0.80 | CYP3A4 (0.50) | CYP3A4ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL23118055 | 0.79 | ABL1 (0.50) | CYP3A4ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL31268471 | 0.79 | CFD (0.51) | ALDH1A1KDM4ETSHRGAARAB9A | |
| SCHEMBL16427664 | 0.79 | CFD (0.51) | ALDH1A1KDM4ETSHRGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970087-A1 | A PROCESS FOR THE PREPARATION OF A METAL SALT OF CLAVULANIC ACID | SMITHKLINE BEECHAM PLC (GB) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998045300-A1 | A PROCESS FOR THE PREPARATION OF A METAL SALT OF CLAVULANIC ACID | SMITHKLINE BEECHAM PLC (GB) | 1998-10-15 | — | — | WO | disclosed |
| EP-0804441-A1 | CLAVULANIC ACID EXTRACTION PROCESS | SMITHKLINE BEECHAM PLC (GB) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996022296-A1 | CLAVULANIC ACID EXTRACTION PROCESS | SMITHKLINE BEECHAM P.L.C. (GB) | 1996-07-25 | — | — | WO | disclosed |