Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27559450 | 0.87 | MEN1 (0.51) | MEN1KMT2APOLBFABP4CREBBP | |
| SCHEMBL1716468 | 0.84 | POLB (0.43) | MEN1KMT2APOLBCREBBPKDM4E | |
| SCHEMBL28576274 | 0.83 | POLB (0.42) | MEN1KMT2APOLBCREBBPKDM4E | |
| SCHEMBL27807548 | 0.83 | POLB (0.42) | MEN1KMT2APOLBCREBBPKDM4E | |
| SCHEMBL8089254 | 0.83 | POLB (0.42) | MEN1KMT2APOLBCREBBPKDM4E | |
| SCHEMBL1829917 | 0.80 | ALDH1A1 (0.54) | MEN1KMT2APOLBKDM4EHTT | |
| Sulfuric Acid SCHEMBL17028780 | 0.79 | POLB (0.39) | MEN1KMT2APOLBCREBBPKDM4E | |
| SCHEMBL29258027 | 0.78 | MEN1 (0.47) | MEN1KMT2APOLBFABP4CREBBP | |
| SCHEMBL25345505 | 0.77 | HTR2A (0.55) | MEN1KMT2AHTR6 | |
| SCHEMBL788705 | 0.75 | MEN1 (0.45) | MEN1KMT2AFABP4KDM4ENQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555537-B1 | Endothelin antagonists | BANYU PHARMA CO LTD (JP) | 2000-11-02 | — | — | EP | disclosed |
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |