SCHEMBL788705

SCHEMBL788705

COn1cc(C)c2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
SLC6A2 P23975 3/20 0.42
KDM4E B2RXH2 3/20 0.41
NQO2 P16083 1/20 0.41
HTR6 P50406 1/20 0.40
GPR3 P46089 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CYP1A2 P05177 1/20 0.39
ALKBH5 Q6P6C2 1/20 0.38
FTO Q9C0B1 1/20 0.38
ENPP1 P22413 1/20 0.38
SLC6A4 P31645 1/20 0.37
FABP4 P15090 1/20 0.37
MAPT P10636 2/20 0.37
ALDH1A1 P00352 1/20 0.37
IMPDH2 P12268 1/20 0.37
NR4A2 P43354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3247223 0.98 MEN1 (0.44) MEN1KMT2ASLC6A2KDM4ENQO2
SCHEMBL788704 0.79 GPR3 (0.37) MEN1KMT2AKDM4EGPR3SMN1; SMN2
SCHEMBL7119517 0.79 IMPDH2 (0.40) MEN1KMT2AGPR3SMN1; SMN2MAPT
SCHEMBL9165246 0.78 ALDH1A1 (0.38) MEN1KMT2AKDM4EGPR3SMN1; SMN2
SCHEMBL28670259 0.78 MEN1 (0.45) MEN1KMT2ASLC6A2KDM4ENQO2
SCHEMBL10064695 0.76 GPR84 (0.43) SLC6A2KDM4ESMN1; SMN2ALDH1A1IMPDH2
SCHEMBL29826894 0.76 ALDH1A1 (0.62) KDM4ESMN1; SMN2MAPTALDH1A1IMPDH2
SCHEMBL20855303 0.76 GPR84 (0.43) MEN1KMT2AKDM4EGPR3SMN1; SMN2
SCHEMBL27559450 0.76 MEN1 (0.51) MEN1KMT2ASLC6A2KDM4ENQO2
SCHEMBL27818053 0.76 MEN1 (0.44) MEN1KMT2ASLC6A2KDM4ENQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114324723-A Qualitative detection method for radish glucosinolates 湖北省农业科学院经济作物研究所 2022-04-12 CN claimed
CN-111601896-A Brassicaceae products containing isothiocyanates and methods of making the same 联邦科学技术研究组织 2020-08-28 CN claimed
US-20200255872-A1 Isothiocyanate containing Brassicaceae Products and Method of Preparation Thereof COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2020-08-13 US claimed
CN-111297931-A Broccoli total effective part extract and preparation method and application thereof 成都市三禾田生物技术有限公司 2020-06-19 CN claimed
US-20160331725-A1 USE OF COMPOUNDS THAT ARE ABLE TO INCREASE THE SERUM IGF-1 LEVEL FOR THE PREPARATION OF A THERAPEUTICAL COMPOSITION FOR TREATMENT OF VARIOUS DISEASE STATES ASSOCIATED WITH A REDUCED IGF-1 SERUM LEVEL IN HUMANS AND ANIMALS VEIJLEN N.V. 2016-11-17 US claimed
JP-4641942-B2 2011-03-02 JP claimed
US-20100281567-A1 TRANSGENIC PLANTS HAVING ALTERED LEVELS OF AROMATIC AMINO ACIDS AND METABOLITES DERIVED THEREFROM YEDA RESEARCH AND DEVELOPMENT CO. LTD AT THE WEIZMANN INSTITUTE OF SCIENCE (IL) 2010-11-04 US claimed
US-20090326056-A1 NOVEL ACTIVES AGAINST PROSTATE CARCINOMA DSM IP ASSETS B.V. (NL) 2009-12-31 US claimed
EP-1569628-B1 NOVEL USE OF LYCOPENE FOR THE TREATMENT OF DISEASES ASSOCIATED WITH ANDROGEN SIGNALLING DSM IP ASSETS BV (NL) 2009-07-22 EP claimed
EP-2020997-A2 NOVEL ACTIVES AGAINST PROSTATE CARCINOMA DSMIP Assets B.V. (NL) 2009-02-11 EP claimed
EP-1670444-A2 USE OF INDOLEACETIC ACID DERIVATIVES WHICH INCREASE THE SERUM IGF-1 LEVEL FOR THE PREPARATION OF A THERAPEUTICAL COMPOSITION FOR TREATMENT OF VARIOUS DISEASES Veijlen N.V. (AN) 2006-06-21 EP claimed
US-20060069151-A1 Novel use of lycopene DSM IP ASSETS B.V. (NL) 2006-03-30 US claimed
US-20060020046-A1 Compositions comprising lycopene for the treatment and prevention of angiogenesis associated pathologies DMS IP ASSETS B.V. (NL) 2006-01-26 US claimed
EP-1569628-A1 NOVEL USE OF LYCOPENE DSM IP Assets B.V. (NL) 2005-09-07 EP claimed
WO-2005039546-A2 USE OF INDOLEACETIC ACID DERIVATIVES WHICH INCREASE THE SERUM IGF-1 LEVEL FOR THE PREPARATION OF A THERAPEUTICAL COMPOSITION FOR TREATMENT OF VARIOUS DISEASES VEIJLEN N.V. (AN) 2005-05-06 WO claimed
EP-1476143-A1 COMPOSITIONS COMPRISING LYCOPENE FOR THE TREATMENT AND PREVENTION OF ANGIOGENESIS ASSOCIATED PATHOLOGIES DSM IP Assets B.V. (NL) 2004-11-17 EP claimed
WO-2004052351-A1 NOVEL USE OF LYCOPENE DSM IP ASSETS B.V. (CH) 2004-06-24 WO claimed
WO-2003068202-A1 COMPOSITIONS COMPRISING LYCOPENE FOR THE TREATMENT AND PREVENTION OF ANGIOGENESIS ASSOCIATED PATHOLOGIES DSM IP ASSETS B.V. (NL) 2003-08-21 WO claimed
US-6399568-B1 ANTICANCER AGENTS JAPAN ENERGY CORPORATION (JP) 2002-06-04 US claimed
EP-1010705-A1 NOVEL CYCLIC TETRAPEPTIDE DERIVATIVES AND MEDICINAL USE THEREOF Japan Energy Corporation (JP) 2000-06-21 EP claimed