Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 12/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089233 | 0.75 | CYP1A2 (0.36) | MKNK1GLACYP1A2CYP2C9LMNA | |
| SCHEMBL8081077 | 0.74 | CYP1A2 (0.33) | CYP1A2CYP2C9LMNAALDH1A1 | |
| SCHEMBL3896575 | 0.73 | ALDH1A1 (0.46) | CYP2C9LMNAALDH1A1MAPT | |
| SCHEMBL11734584 | 0.73 | CYP1A2 (0.43) | MKNK1GLACYP1A2CYP2C9LMNA | |
| SCHEMBL29752552 | 0.73 | ALDH1A1 (0.46) | CYP2C9LMNAALDH1A1MAPT | |
| SCHEMBL7983668 | 0.72 | CYP1A2 (0.39) | MKNK1CYP1A2CYP2C9 | |
| SCHEMBL2994158 | 0.72 | ALDH1A1 (0.42) | CYP1A2CYP2C9LMNAALDH1A1MAPT | |
| SCHEMBL8081113 | 0.72 | ALDH1A1 (0.38) | CYP2C9LMNAALDH1A1MAPT | |
| SCHEMBL8503271 | 0.72 | ALDH1A1 (0.40) | CYP1A2CYP2C9LMNAALDH1A1MAPT | |
| SCHEMBL2992903 | 0.71 | LMNA (0.39) | CYP1A2CYP2C9LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043242-A | TREATING A MAMMAL AFFLICTED WITH A DISEASE BASED ON HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0946559-A2 | IMIDAZOPYRIDAZINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028299-A2 | IMIDAZOPYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-07-02 | — | — | WO | disclosed |