Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 11/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092902 | 0.80 | PTGS2 (0.70) | PTGS1PTGS2ALOX5 | |
| SCHEMBL11067689 | 0.76 | KMT2A (0.64) | PTGS1PTGS2MEN1KMT2ARECQL | |
| SCHEMBL8349771 | 0.74 | PTGS1 (0.45) | PTGS1PTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL8759810 | 0.73 | PTGS2 (1.00) | PTGS1PTGS2ALOX5 | |
| SCHEMBL8759670 | 0.71 | PTGS2 (0.86) | PTGS1PTGS2THRBALOX5 | |
| SCHEMBL10428438 | 0.71 | MEN1 (0.56) | MEN1KMT2ARECQLALDH1A1POLB | |
| SCHEMBL8759729 | 0.69 | PTGS2 (0.73) | PTGS1PTGS2ALOX5 | |
| SCHEMBL15354269 | 0.68 | ALDH1A1 (1.00) | MEN1KMT2ARECQLALDH1A1POLB | |
| SCHEMBL6672311 | 0.67 | PTGS1 (0.53) | PTGS1PTGS2ALOX5 | |
| SCHEMBL6642062 | 0.67 | PTGS1 (0.53) | PTGS1PTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107311-A | ANALGESICS | THE PROCTER & GAMBLE COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| US-5750543-A | ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1998-05-12 | — | — | US | disclosed |