Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.64 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12303418 | 1.00 | RORC (0.64) | RORCCCR5FUCA1GRIN2BKDM1A | |
| SCHEMBL12303419 | 1.00 | RORC (0.64) | RORCCCR5FUCA1GRIN2BKDM1A | |
| SCHEMBL8089289 | 1.00 | RORC (0.64) | RORCCCR5FUCA1GRIN2BKDM1A | |
| SCHEMBL15121585 | 0.92 | RORC (0.62) | RORCFUCA1GRIN2B | |
| SCHEMBL1342948 | 0.92 | RORC (0.62) | RORCFUCA1GRIN2B | |
| SCHEMBL1343829 | 0.92 | RORC (0.62) | RORCFUCA1GRIN2B | |
| SCHEMBL1443541 | 0.92 | RORC (0.62) | RORCFUCA1GRIN2B | |
| SCHEMBL1713810 | 0.91 | RORC (0.61) | RORCFUCA1GRIN2BKDM4E | |
| SCHEMBL1713857 | 0.91 | RORC (0.61) | RORCFUCA1GRIN2BKDM4E | |
| SCHEMBL1714493 | 0.91 | RORC (0.61) | RORCFUCA1GRIN2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166037-A | Pyrrolidine and piperidine modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2000-12-26 | — | — | US | disclosed |