Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081242 | 0.87 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL8089262 | 0.86 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL9199820 | 0.86 | PPARG (0.57) | AGTR1AGTR2 | |
| SCHEMBL9133442 | 0.85 | AGTR1 (0.69) | AGTR1AGTR2 | |
| SCHEMBL7942058 | 0.85 | AGTR1 (0.78) | AGTR1AGTR2 | |
| SCHEMBL29486799 | 0.84 | AGTR1 (0.77) | AGTR1AGTR2 | |
| SCHEMBL8094903 | 0.83 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL8088469 | 0.83 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9409773 | 0.82 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL9571451 | 0.82 | AGTR1 (0.65) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037349-A | HAVING ANTAGONISTIC PROPERTIES TOWARDS ANGIOTENSIN II CAN BE USED FOR THE TREATMENT OF HYPERTENSION, ALDOSTERONISM AND CARDIAC INSUFFICIENCY | MERCK PATENT GMBH (DE) | 2000-03-14 | — | — | US | disclosed |