SCHEMBL9409773

SCHEMBL9409773

CCCCc1nc2ccn(Cc3ccccc3C(=O)OC)c(=O)c2n1Cc1ccc(-c2ccsc2C#N)cc1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 18/20 0.60
AGTR2 P50052 18/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9178184 0.84 AGTR1 (0.61) AGTR1AGTR2
SCHEMBL8081205 0.83 AGTR2 (0.64) AGTR1AGTR2
SCHEMBL8089291 0.82 AGTR1 (0.73) AGTR1AGTR2
SCHEMBL9265644 0.81 AGTR1 (0.69) AGTR1AGTR2
SCHEMBL9571451 0.77 AGTR1 (0.65) AGTR1AGTR2
SCHEMBL8089262 0.76 AGTR1 (0.71) AGTR1AGTR2
SCHEMBL8094974 0.76 AGTR2 (0.73) AGTR1AGTR2
SCHEMBL8081242 0.76 AGTR1 (0.66) AGTR1AGTR2
SCHEMBL7014291 0.76 AGTR2 (0.52) AGTR1AGTR2
SCHEMBL8092770 0.75 AGTR2 (0.57) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0595151-A2 Imidazopyridine derivates as antagonists of angiotensin II MERCK PATENT GmbH (DE) 1994-05-04 EP claimed