Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4308808 | 0.82 | ALDH1A1 (0.50) | TSHRTYMSKDM4EALDH1A1SIRT2 | |
| SCHEMBL18586340 | 0.79 | KMT2A (0.39) | MAPTHSD17B10KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL31162515 | 0.79 | POLB (0.41) | POLBMAPTMAP4K4EGFRHSD17B10 | |
| SCHEMBL2536197 | 0.77 | MAP4K4 (0.41) | POLBMAPTMAP4K4EGFRHSD17B10 | |
| SCHEMBL31098957 | 0.75 | SIRT2 (0.41) | TYMSEGFRKDM4EALDH1A1SIRT2 | |
| SCHEMBL1283842 | 0.74 | CHRM5 (0.50) | POLBMAPTL3MBTL1NOX1 | |
| SCHEMBL13985851 | 0.73 | MAP4K4 (0.39) | POLBMAPTMAP4K4EGFRHSD17B10 | |
| SCHEMBL6098360 | 0.73 | POLB (0.44) | POLBMAPTMAP4K4EGFRHSD17B10 | |
| SCHEMBL9056033 | 0.72 | POLB (0.34) | POLBMAPTMAP4K4HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL2539026 | 0.72 | MAP4K4 (0.38) | POLBMAPTMAP4K4EGFRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1105720-C | Imidazopyridazines compound | AOTANNA MEDICINE AG (DE) | 2003-04-16 | — | — | CN | disclosed |
| US-6043242-A | TREATING A MAMMAL AFFLICTED WITH A DISEASE BASED ON HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-03-28 | — | — | US | disclosed |
| CN-1246120-A | Imidazopyridazines compound | BYK GULDEN LOMBERG CHEM FAB (DE) | 2000-03-01 | — | — | CN | disclosed |
| EP-0946559-A2 | IMIDAZOPYRIDAZINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028299-A2 | IMIDAZOPYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-07-02 | — | — | WO | disclosed |