Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 11/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089293 | 0.82 | POLB (0.41) | ALDH1A1KDM4ESIRT2APPTSHR | |
| SCHEMBL9480589 | 0.82 | KDM4E (0.47) | ALDH1A1KDM4ESIRT2CHRM5CHKA | |
| SCHEMBL4313244 | 0.81 | KDM4E (0.41) | ALDH1A1KDM4ESIRT2CHRM5CHKA | |
| SCHEMBL31098957 | 0.80 | SIRT2 (0.41) | ALDH1A1KDM4ESIRT2CHKATYMS | |
| SCHEMBL29907776 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4ESIRT2CHRM5CHKA | |
| SCHEMBL15211555 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4ESIRT2CHRM5CHKA | |
| SCHEMBL4307694 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4ESIRT2CHRM5CHKA | |
| SCHEMBL15212887 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4ESIRT2CHRM5CHKA | |
| SCHEMBL31182983 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4ESIRT2CHRM5CHKA | |
| SCHEMBL7664616 | 0.80 | KDM4E (0.50) | ALDH1A1KDM4ESIRT2CHRM5CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104937493-B | Composition for forming resist upper layer film for lithography and method for manufacturing semiconductor device | 日产化学工业株式会社 | 2019-11-08 | — | — | CN | disclosed |
| CN-110218189-A | A kind of simple and convenient process for preparing of Abbe Seeley intermediate and Abbe Seeley | 新发药业有限公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-106458880-B | Organic selenium compound, preparation method and its medicinal usage especially as antitumor agent | 特瑞海德公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-109311861-A | Process for producing diphenylmethane derivative | 株式会社大熊制药 | 2019-02-05 | — | — | CN | disclosed |
| CN-106687471-B | 3-Nitrogen or Sulfur substituted estra-1, 3,5(10), 16-tetraene AKR1C3 inhibitors | 拜耳医药股份公司 | 2018-10-30 | — | — | CN | disclosed |
| CN-108524529-A | Acid-sensitive adriamycin prodrug based on zwitterion and folic acid targeting as well as preparation method and application thereof | 苏州大学 | 2018-09-14 | — | — | CN | disclosed |
| CN-105732590-B | Pyrimido saturated fat ring diamine compounds and application thereof | 华东理工大学 | 2018-07-24 | — | — | CN | disclosed |
| CN-105237560-B | A kind of LZC696 intermediates and its synthetic method | 上海博氏医药科技有限公司 | 2018-07-06 | — | — | CN | disclosed |
| CN-104812263-B | The manufacture method of secure component and secure component | 地方独立行政法人京都市产业技术研究所 | 2017-11-10 | — | — | CN | disclosed |
| CN-104530413-B | A kind of bio-related substance of multiple functionalized H types polyethyleneglycol derivative modification | 厦门赛诺邦格生物科技股份有限公司 | 2017-08-25 | — | — | CN | disclosed |
| US-20090044345-A1 | Use of Metal Complex Compounds as Oxidation Catalysts | CIBA CORP. | 2009-02-19 | — | — | US | disclosed |
| US-20090044345-A1 | Use of Metal Complex Compounds as Oxidation Catalysts | CIBA CORP. | 2009-02-19 | — | — | US | disclosed |
| US-20090044345-A1 | Use of Metal Complex Compounds as Oxidation Catalysts | CIBA CORP. | 2009-02-19 | — | — | US | disclosed |
| EP-1981635-A1 | USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | Ciba Holding Inc. (CH) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007090461-A1 | USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | CIBA HOLDING INC. (CH) | 2007-08-16 | — | — | WO | disclosed |
| WO-2007090461-A1 | USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | CIBA HOLDING INC. (CH) | 2007-08-16 | — | — | WO | disclosed |
| CN-1219936-A | New triazolopurines, method of preparing them and their use as drugs | BOEHRINGER INGELHEIM KG (DE) | 1999-06-16 | — | — | CN | disclosed |
| CN-86107742-A | Quaternary ammoniated 2-position has the substituent carbon of assorted sulfane sulphur for the mould alkene of cyanogen | — | 1987-08-12 | — | — | CN | disclosed |
| EP-0200777-A1 | NEW AMINO COMPOUNDS, PREPARATION PROCESS THEREOF, UTILIZATION THEREOF AND DRUGS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1986-11-12 | — | — | EP | disclosed |
| WO-1986002645-A1 | NEW AMINO COMPOUNDS, PREPARATION PROCESS THEREOF, UTILIZATION THEREOF AND DRUGS CONTAINING THEM | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT M (DE) | 1986-05-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090044345-A1 | Use of Metal Complex Compounds as Oxidation Catalysts | MT-CO2, MT-CO1, SOD1 | ALDH1A1 984/4885KDM4E 3219/4885SIRT2 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.