Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.56 |
| ▸ | CTSS | P25774 | 7/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089323 | 1.00 | CTSK (0.56) | CTSKCTSSCTSLCTSB | |
| SCHEMBL8185522 | 0.95 | CTSK (0.60) | CTSKCTSS | |
| SCHEMBL6654092 | 0.89 | CTSK (0.58) | CTSKCTSSCTSLCTSB | |
| SCHEMBL8183200 | 0.87 | CTSK (0.45) | CTSKCTSSCTSLCTSB | |
| SCHEMBL2508772 | 0.86 | CTSS (0.50) | CTSKCTSSCTSLCTSB | |
| SCHEMBL30788788 | 0.86 | CTSK (0.51) | CTSKCTSS | |
| SCHEMBL15186434 | 0.82 | CTSK (0.49) | CTSKCTSS | |
| SCHEMBL5958657 | 0.82 | CTSK (0.56) | CTSKCTSSCTSLCTSB | |
| SCHEMBL15259348 | 0.82 | CTSK (0.56) | CTSKCTSSCTSLCTSB | |
| SCHEMBL30788772 | 0.82 | CTSK (0.47) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555537-B1 | Endothelin antagonists | BANYU PHARMA CO LTD (JP) | 2000-11-02 | — | — | EP | disclosed |
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |